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Ctnnb1tm2.1Kem
Targeted Allele Detail
Nomenclature
Symbol: Ctnnb1tm2.1Kem
Name: catenin (cadherin associated protein), beta 1; targeted mutation 2.1 Rolf Kemler
MGI ID: MGI:2148569
Synonyms: beta-catenindel, Ctnnb1Del, floxdel
Gene: Ctnnb1  Location: Chr9:120929216-120960507 bp, + strand  Genetic Position: Chr9, 72.19 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67966
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele is a derivative of Catnbtm2Kem in which Cre mediated recombination removed exons 2 through 6. (J:67966)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctnnb1 Mutation:  17 strains or lines available
References
Original:  J:67966 Brault V, et al., Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development. 2001 Apr;128(8):1253-64
All:  38 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory