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Gaatm1Rabn
Targeted Allele Detail
Nomenclature
Symbol: Gaatm1Rabn
Name: glucosidase, alpha, acid; targeted mutation 1, Nina Raben
MGI ID: MGI:2148550
Synonyms: 6neo, Gaa-
Gene: Gaa  Location: Chr11:119267887-119285454 bp, + strand  Genetic Position: Chr11, 83.35 cM, cytoband D-E
Abnormal lysosomal glycogen storage in heart and skeletal muscle of Gaatm1Rabn/Gaatm1Rabn mice

Show the 3 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48839
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (knock-out)
Mutation:    Insertion
 
Mutation details
Phenotypes
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Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gaa Mutation:  8 strains or lines available
References
Original:  J:48839 Raben N, et al., Targeted disruption of the acid alpha-glucosidase gene in mice causes an illness with critical features of both infantile and adult human glycogen storage disease type II. J Biol Chem. 1998 Jul 24;273(30):19086-92
All:  30 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory