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Gene trapped Allele Detail
Symbol: DmdGt(ROSABetageo)1Mpd
Name: dystrophin, muscular dystrophy; gene trap 1, Karin Wertz
MGI ID: MGI:2148259
Synonyms: Dmdmdx-betageo, mdx-betageo
Gene: Dmd  Location: ChrX:82948870-85206141 bp, + strand  Genetic Position: ChrX, 38.38 cM, cytoband C
Germline Transmission:  Earliest citation of germline transmission: J:47968
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector
Mutation detailsInsertion of a gene trap vector resulted in aberrant splicing from exon 63 to the inserted Beta-geo gene. RT-PCR analysis demonstrated that the mRNA was mutated in this allele, although a very low level of wild-type transcript was detected in brain. Full length wild-type protein could not be detected by Western blotting in tissue extracts derived from hemizygous males. (J:47968)
View phenotypes for all genotypes (concatenated display).
Disease models
In Mice Carrying this Mutation: 57 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dmd Mutation:  156 strains or lines available
Original:  J:47968 Wertz K, et al., Dmd(mdx-beta geo): a new allele for the mouse dystrophin gene. Dev Dyn. 1998 Jun;212(2):229-41
All:  3 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory