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Aplp2tm1Min
Targeted Allele Detail
Nomenclature
Symbol: Aplp2tm1Min
Name: amyloid beta (A4) precursor-like protein 2; targeted mutation 1, Minoo Rassoulzadegan
MGI ID: MGI:2138038
Gene: Aplp2  Location: Chr9:31149557-31211815 bp, - strand  Genetic Position: Chr9, 16.66 cM, cytoband A2-B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:49466
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced sequences between exon 4 and exon 15, deleting 11.35 kb of the gene. (J:49466)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aplp2 Mutation:  16 strains or lines available
References
Original:  J:49466 Rassoulzadegan M, et al., APLP2, a member of the Alzheimer precursor protein family, is required for correct genomic segregation in dividing mouse cells. EMBO J. 1998 Aug 17;17(16):4647-56
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory