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Thrbtm1.1Syc
Targeted Allele Detail
Nomenclature
Symbol: Thrbtm1.1Syc
Name: thyroid hormone receptor beta; targeted mutation 1.1, Sheue-yann Cheng
MGI ID: MGI:2137592
Synonyms: TRbetaPV, TRbetaPV, TRbeta PV
Gene: Thrb  Location: Chr14:17660960-18038086 bp, + strand  Genetic Position: Chr14, 7.08 cM, cytoband A3
Histology of thyroid glands of wild-type, Thrbtm1.1Syc/Thrb+ and Thrbtm1.1Syc/Thrbtm1.1Syc mice.

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65885
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Thrb Mutation:  3 strains or lines available
References
Original:  J:65885 Kaneshige M, et al., Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone. Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13209-14
All:  52 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory