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Rettm2.1Cos
Targeted Allele Detail
Nomenclature
Symbol: Rettm2.1Cos
Name: ret proto-oncogene; targeted mutation 2.1, Frank Costantini
MGI ID: MGI:2136896
Synonyms: retMEN2B
Gene: Ret  Location: Chr6:118151748-118197744 bp, - strand  Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60659
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Single point mutation
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ret Mutation:  24 strains or lines available
References
Original:  J:60659 Smith-Hicks CL, et al., C-cell hyperplasia, pheochromocytoma and sympathoadrenal malformation in a mouse model of multiple endocrine neoplasia type 2B. EMBO J. 2000 Feb 15;19(4):612-22
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory