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Gdnftm2Bbd
Targeted Allele Detail
Nomenclature
Symbol: Gdnftm2Bbd
Name: glial cell line derived neurotrophic factor; targeted mutation 2, Mariano Barbacid
MGI ID: MGI:2136845
Synonyms: Gdnf-, GDNF/neo
Gene: Gdnf  Location: Chr15:7811011-7837575 bp, + strand  Genetic Position: Chr15, 3.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:33809
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of exon 2 with a neomycin cassette. (J:33809)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gdnf Mutation:  5 strains or lines available
References
Original:  J:33809 Sanchez MP, et al., Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature. 1996 Jul 4;382(6586):70-3
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory