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Irs1tm1Tka
Targeted Allele Detail
Nomenclature
Symbol: Irs1tm1Tka
Name: insulin receptor substrate 1; targeted mutation 1, Takashi Kadowaki
MGI ID: MGI:2136643
Synonyms: IRS-1-
Gene: Irs1  Location: Chr1:82233101-82291416 bp, - strand  Genetic Position: Chr1, 42.0 cM, cytoband C5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:21373
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Irs1 Mutation:  3 strains or lines available
References
Original:  J:21373 Tamemoto H, et al., Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1 [see comments]. Nature. 1994 Nov 10;372(6502):182-6
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory