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Fgfr3tm2Wei
Targeted Allele Detail
Nomenclature
Symbol: Fgfr3tm2Wei
Name: fibroblast growth factor receptor 3; targeted mutation 2, Weizmann Institute of Science
MGI ID: MGI:2135636
Synonyms: Fgfr3G374R, FGFR3G374Rneo-
Gene: Fgfr3  Location: Chr5:33721724-33737067 bp, + strand  Genetic Position: Chr5, 17.83 cM, cytoband B
Anatomical defects of the Fgfr3tm2Wei/Fgfr3+ mouse

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:54829
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Single point mutation
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr3 Mutation:  7 strains or lines available
References
Original:  J:54829 Wang Y, et al., A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4455-60
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory