About   Help   FAQ
Pitx1tm1Rsd
Targeted Allele Detail
Summary
Symbol: Pitx1tm1Rsd
Name: paired-like homeodomain transcription factor 1; targeted mutation 1, Michael G Rosenfeld
MGI ID: MGI:1934200
Gene: Pitx1  Location: Chr13:55972864-55984005 bp, - strand  Genetic Position: Chr13, 30.06 cM
Alliance: Pitx1tm1Rsd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:53310
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe sequences encoding the homeodomain and most of the 3' coding sequence of this gene were replaced with a lacZ/neo-derived cassette via homologous recombination. (J:53310)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 3 assay results
2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 18 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pitx1 Mutation:  10 strains or lines available
References
Original:  J:53310 Szeto DP, et al., Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development. Genes Dev. 1999 Feb 15;13(4):484-94
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory