About   Help   FAQ
Notch2tm1Grid
Targeted Allele Detail
Nomenclature
Symbol: Notch2tm1Grid
Name: notch 2; targeted mutation 1, Tom Gridley
MGI ID: MGI:1933205
Synonyms: Notch2-, Notch2del1
Gene: Notch2  Location: Chr3:98013538-98150367 bp, + strand  Genetic Position: Chr3, 42.42 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67157
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Hypomorph)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 38 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Notch2 Mutation:  19 strains or lines available
References
Original:  J:67157 McCright B, et al., Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory