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F9tm1Emg
Targeted Allele Detail
Summary
Symbol: F9tm1Emg
Name: coagulation factor IX; targeted mutation 1, Erlinda M Gordon
MGI ID: MGI:1932244
Synonyms: F. IX
Gene: F9  Location: ChrX:59044824-59076119 bp, + strand  Genetic Position: ChrX, 33.5 cM, cytoband A6-A7
Alliance: F9tm1Emg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48501
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin cassette replaced 3.2 kb of sequence spanning exons g and h. Neither RT-PCR and Northern blot analyses detected mRNA in homozygous mutant mice. (J:48501)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any F9 Mutation:  8 strains or lines available
References
Original:  J:48501 Kundu RK, et al., Targeted inactivation of the coagulation factor IX gene causes hemophilia B in mice. Blood. 1998 Jul 1;92(1):168-74
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory