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Il13tm1.1Anjm
Targeted Allele Detail
Nomenclature
Symbol: Il13tm1.1Anjm
Name: interleukin 13; targeted mutation 1.1, Andrew NJ McKenzie
MGI ID: MGI:1931822
Synonyms: IL-13-, IL-13- creed
Gene: Il13  Location: Chr11:53631324-53634702 bp, - strand  Genetic Position: Chr11, 31.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67965
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsAn IRES-lacZ cassette was inserted into exon 1. An adjacent loxP flanked neomycin resistance gene was removed in ES cells prior to blastocyst injection, leaving a single loxP site in the final allele. (J:67965)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il13 Mutation:  21 strains or lines available
References
Original:  J:67965 McKenzie GJ, et al., Impaired development of Th2 cells in IL-13-deficient mice. Immunity. 1998 Sep;9(3):423-32
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory