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F5tm1Dgi
Targeted Allele Detail
Nomenclature
Symbol: F5tm1Dgi
Name: coagulation factor V; targeted mutation 1, David Ginsburg
MGI ID: MGI:1931525
Synonyms: Fv-
Gene: F5  Location: Chr1:164151838-164220277 bp, + strand  Genetic Position: Chr1, 71.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:36444
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of exons 8-11 with a neomycin cassette. (J:36444)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any F5 Mutation:  117 strains or lines available
References
Original:  J:36444 Cui J, et al., Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V. Nature. 1996 Nov 7;384(6604):66-8
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory