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Targeted Allele Detail
Symbol: Nkx3-2tm1Bobh
Name: NK3 homeobox 2; targeted mutation 1, Robert E Hill
MGI ID: MGI:1931319
Synonyms: Bapx1 -, Nkx3.2 -
Gene: Nkx3-2  Location: Chr5:41761483-41764220 bp, - strand  Genetic Position: Chr5, 22.58 cM
Skeletal phenotypes of E18.5 Nkx3-2tm1Bobh/Nkx3-2tm1Bobh fetuses

Show the 3 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:57112
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Insertion of a neomycin cassette into the coding region of exon 1. (J:57112)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 21 assay results
In Structures Affected by this Mutation: 23 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nkx3-2 Mutation:  15 strains or lines available
Original:  J:57112 Lettice LA, et al., The mouse bagpipe gene controls development of axial skeleton, skull, and spleen. Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9695-700
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory