Pax6^Coop
Chemically induced Allele Detail

Summary

• Symbol: Pax6^Coop
• Name: paired box 6; corneal opacity
• MGI ID: MGI:1931308
• Synonyms: ENU-4002
• Gene: Pax6 Location: Chr2:105499245-105527709 bp, + strand Genetic Position: Chr2, 55.31 cM
• Alliance: Pax6^Coop page

Mutation origin

• Strain of Origin: DBA/2

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The C to T transition at position 1033 of the encoded mRNA creates a premature stop codon, resulting in a truncated protein. (J:66649)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax6 Mutation: 90 strains or lines available

References

• Original: J:63651 Favor J, et al., Saturation mutagenesis for dominant eye morphological defects in the mouse Mus musculus. Mamm Genome. 2000 Jul;11(7):520-5
• All: 2 reference(s)