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Csf2tm1Mlg
Targeted Allele Detail
Summary
Symbol: Csf2tm1Mlg
Name: colony stimulating factor 2 (granulocyte-macrophage); targeted mutation 1, Richard C Mulligan
MGI ID: MGI:1930996
Synonyms: Csf2-, Csf2tm1Jaw, GM-, GM-CSF-, GM-CSF KO
Gene: Csf2  Location: Chr11:54138097-54140493 bp, - strand  Genetic Position: Chr11, 32.13 cM
Alliance: Csf2tm1Mlg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:17978
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 3 and 4 and flanking intronic sequence were replaced by a neomycin cassette. (J:17978)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 11 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Csf2tm1Mlg
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Csf2 Mutation:  33 strains or lines available
References
Original:  J:17978 Dranoff G, et al., Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science. 1994 Apr 29;264(5159):713-6
All:  91 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory