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Uchl3tm1Tilg
Targeted Allele Detail
Nomenclature
Symbol: Uchl3tm1Tilg
Name: ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); targeted mutation 1, Shirley M Tilghman
MGI ID: MGI:1930988
Synonyms: Uch-L3delta3-7
Gene: Uchl3  Location: Chr14:101653967-101696124 bp, + strand  Genetic Position: Chr14, 50.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:61093
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of exons 3 - 7, which encode ~90% of the protein, with a neomycin cassette. (J:61093)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Uchl3 Mutation:  23 strains or lines available
References
Original:  J:61093 Kurihara LJ, et al., Expression and functional analysis of Uch-L3 during mouse development. Mol Cell Biol. 2000 Apr;20(7):2498-504
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory