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Bdnftm1Gdy
Targeted Allele Detail
Summary
Symbol: Bdnftm1Gdy
Name: brain derived neurotrophic factor; targeted mutation 1, George D Yancopoulos
MGI ID: MGI:1930038
Synonyms: bdnf-
Gene: Bdnf  Location: Chr2:109505045-109557352 bp, + strand  Genetic Position: Chr2, 56.63 cM
Alliance: Bdnftm1Gdy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:25565
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    332bp of the gene was deleted and replaced by a neomycin cassette. (J:25565)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bdnf Mutation:  38 strains or lines available
References
Original:  J:25565 Conover JC, et al., Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4. Nature. 1995 May 18;375(6528):235-8
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory