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Erbb4tm1Grl
Targeted Allele Detail
Nomenclature
Symbol: Erbb4tm1Grl
Name: erb-b2 receptor tyrosine kinase 4; targeted mutation 1, Greg Lemke
MGI ID: MGI:1929607
Synonyms: ErbB4-
Gene: Erbb4  Location: Chr1:68032186-69108059 bp, - strand  Genetic Position: Chr1, 33.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:29972
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsThe gene was disrupted by insertion of a neomycin cassete into exon 2. Resulting mRNA from this allele splices exon 1 to exon 3, introducing a frameshift mutation. (J:29972)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Erbb4 Mutation:  41 strains or lines available
References
Original:  J:29972 Gassmann M, et al., Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor [see comments]. Nature. 1995 Nov 23;378(6555):390-4
All:  33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory