About   Help   FAQ
Ebf1tm1Rug
Targeted Allele Detail
Nomenclature
Symbol: Ebf1tm1Rug
Name: early B cell factor 1; targeted mutation 1, Rudolf Grosschedl
MGI ID: MGI:1928729
Synonyms: EBF-, Ebf1-, O/E-1-
Gene: Ebf1  Location: Chr11:44618100-45008096 bp, + strand  Genetic Position: Chr11, 26.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:52607
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A PGK-neomycin cassette replaced exon 3, which encodes the DNA-binding domain. (J:52607)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 103 assay results
In Structures Affected by this Mutation: 16 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ebf1 Mutation:  26 strains or lines available
References
Original:  J:52607 Lin H, et al., Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature. 1995 Jul 20;376(6537):263-7
All:  33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory