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Targeted Allele Detail
Symbol: Grin2atm1Rsp
Name: glutamate receptor, ionotropic, NMDA2A (epsilon 1); targeted mutation 1, Rolf Sprengel
MGI ID: MGI:1928287
Synonyms: NR2AdeltaC
Gene: Grin2a  Location: Chr16:9567898-9995560 bp, - strand  Genetic Position: Chr16, 5.28 cM
Germline Transmission:  Earliest citation of germline transmission: J:45446
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExpression of a receptor lacking the intracellular C-terminal domain by insertion of a PGK-neomycin cassette 3' to the M4 transmembrane coding region, with translation stop codons in three frames. (J:45446)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grin2a Mutation:  46 strains or lines available
Original:  J:45446 Sprengel R, et al., Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell. 1998 Jan 23;92(2):279-89
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory