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Targeted Allele Detail
Symbol: Fgf10tm1Wss
Name: fibroblast growth factor 10; targeted mutation 1, W Scott Simonet
MGI ID: MGI:1927833
Synonyms: Fgf-10-, Fgf10-, fgf10neo
Gene: Fgf10  Location: Chr13:118669791-118792115 bp, + strand  Genetic Position: Chr13, 67.14 cM, cytoband A3-A4
Palatal abnormalities in Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn and Fgf10tm1Wss/Fgf10tm1Wss mice

Show the 3 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:50768
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of part of exon 1 containing the transcription start site with a PGK-neomycin cassette (J:50768)
View phenotypes for all genotypes (concatenated display).
In Mice Carrying this Mutation: 76 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf10 Mutation:  7 strains or lines available
Original:  J:50768 Min H, et al., Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev. 1998 Oct 15;12(20):3156-61
All:  34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory