About   Help   FAQ
Fgf10tm1Wss
Targeted Allele Detail
Summary
Symbol: Fgf10tm1Wss
Name: fibroblast growth factor 10; targeted mutation 1, W Scott Simonet
MGI ID: MGI:1927833
Synonyms: Fgf-10-, Fgf10-, fgf10neo
Gene: Fgf10  Location: Chr13:118851199-118928651 bp, + strand  Genetic Position: Chr13, 67.14 cM, cytoband A3-A4
Alliance: Fgf10tm1Wss page
Palatal abnormalities in Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn and Fgf10tm1Wss/Fgf10tm1Wss mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:50768
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of part of exon 1 containing the transcription start site with a PGK-neomycin cassette (J:50768)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 52115 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 41 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf10 Mutation:  33 strains or lines available
References
Original:  J:50768 Min H, et al., Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev. 1998 Oct 15;12(20):3156-61
All:  47 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory