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Nf2tm2.1Gth
Targeted Allele Detail
Nomenclature
Symbol: Nf2tm2.1Gth
Name: neurofibromatosis 2; targeted mutation 2.1, Gilles Thomas
MGI ID: MGI:1926957
Synonyms: Nf2delta2
Gene: Nf2  Location: Chr11:4765845-4849536 bp, - strand  Genetic Position: Chr11, 3.0 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63264
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele is a derivative of Nf2tm2Gth in which a Cre mediated recombination event in the germline removed exon 2. (J:63264)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nf2 Mutation:  47 strains or lines available
References
Original:  J:63264 Giovannini M, et al., Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2. Genes Dev. 2000 Jul 1;14(13):1617-30
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory