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Targeted Allele Detail
Symbol: Ring1tm1Mvi
Name: ring finger protein 1; targeted mutation 1, Miguel Vidal
MGI ID: MGI:1926913
Synonyms: Ring1A-
Gene: Ring1  Location: Chr17:34020792-34024680 bp, - strand  Genetic Position: Chr17, 17.98 cM
Germline Transmission:  Earliest citation of germline transmission: J:65300
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsDeletion of the first six exons, including the sequences encoding the translation initiation start site, the RING finger domain, the homology domain 2 and part of the homology domain 3. These sequences were replaced with an HPRT minigene. (J:65300)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ring1 Mutation:  4 strains or lines available
Original:  J:65300 del Mar Lorente M, et al., Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice. Development. 2000 Dec;127(23):5093-100
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.10
The Jackson Laboratory