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Cdkn2atm1Cjs
Targeted Allele Detail
Nomenclature
Symbol: Cdkn2atm1Cjs
Name: cyclin-dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr
MGI ID: MGI:1926877
Synonyms: ARF-, p19Arf-, p19ARF-, p19Arf-null
Gene: Cdkn2a  Location: Chr4:89274471-89294653 bp, - strand  Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
Abnormal retrolental tissue present in the eyes of neonatal Cdkn2atm1Cjs/Cdkn2atm1Cjs mice

Show the 6 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:44427
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Cdkn2a Mutation:  25 strains or lines available
References
Original:  J:44427 Kamijo T, et al., Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell. 1997 Nov 28;91(5):649-59
All:  117 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory