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Gfra2tm1Msa
Targeted Allele Detail
Nomenclature
Symbol: Gfra2tm1Msa
Name: glial cell line derived neurotrophic factor family receptor alpha 2; targeted mutation 1, Matti S Airaksinen
MGI ID: MGI:1926440
Synonyms: Gfra2-, Gfralpha-2-, Gfralpha2-, GFRalpha2-KO
Gene: Gfra2  Location: Chr14:70890130-70979838 bp, + strand  Genetic Position: Chr14, 36.79 cM, cytoband D3-E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:53284
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of part of first coding exon of the gene with PGK-neomycin cassette. (J:53284)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gfra2 Mutation:  1 strain or line available
References
Original:  J:53284 Rossi J, et al., Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor. Neuron. 1999 Feb;22(2):243-52
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory