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Targeted Allele Detail
Symbol: Ndst2tm1Rls
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2; targeted mutation 1, Richard L Stevens
MGI ID: MGI:1913286
Synonyms: NDST-2-null
Gene: Ndst2  Location: Chr14:20723730-20734562 bp, - strand  Genetic Position: Chr14, 11.53 cM, cytoband B
Germline Transmission:  Earliest citation of germline transmission: J:57120
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsReplacement of amino acids 539 to 580 with a neomycin resistance gene and the introduction of a premature stop codon after residue 538. (J:57120)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ndst2 Mutation:  15 strains or lines available
Original:  J:57120 Humphries DE, et al., Heparin is essential for the storage of specific granule proteases in mast cells [see comments]. Nature. 1999 Aug 19;400(6746):769-72
All:  4 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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