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Targeted Allele Detail
Symbol: Jph2tm1Hta
Name: junctophilin 2; targeted mutation 1, Hiroshi Takeshima
MGI ID: MGI:1891502
Synonyms: JP-2-
Gene: Jph2  Location: Chr2:163336242-163397949 bp, - strand  Genetic Position: Chr2, 84.22 cM, cytoband H3
Germline Transmission:  Earliest citation of germline transmission: J:63879
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe protein-coding sequences of the first exon and part of the first intron were replaced with a neomycin cassette. Immunoblot analysis on total protein from embryonic heart demonstrated that no detectable protein was expressed from this allele. (J:63879)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 3 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jph2 Mutation:  6 strains or lines available
Original:  J:63879 Takeshima H, et al., Junctophilins: a novel family of junctional membrane complex proteins. Mol Cell. 2000 Jul;6(1):11-22
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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