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Nrg3ska
Spontaneous Allele Detail
Nomenclature
Symbol: Nrg3ska
Name: neuregulin 3; scaramanga
MGI ID: MGI:1889610
Synonyms: ska
Gene: Nrg3  Location: Chr14:38368952-39473088 bp, - strand  Genetic Position: Chr14, 22.18 cM, cytoband B
Mammary gland abnormalities in Nrg3ska/Nrg3ska mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  A/J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Duplication
 
Mutation detailsThis allele maps to an interval between the microsatellite markers D14Mit14 and D14Mit80 located at 10.0 cM and 13.5 cM. The mutation identified is a microsatellite repeat within intron 7 of the gene. This simple sequence repeat (SSR) was found to completely cosegregate with the ska phenotype. (J:100495)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 13 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 21 strains available      Cell Lines: 0 lines available
Carrying any Nrg3 Mutation:  21 strains or lines available
References
Original:  J:60708 Howard BA, et al., The characterization of a mouse mutant that displays abnormal mammary gland development. Mamm Genome. 2000 Mar;11(3):234-7
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory