Kif5c^tm1Noh
Targeted Allele Detail

Summary

• Symbol: Kif5c^tm1Noh
• Name: kinesin family member 5C; targeted mutation 1, Nobutaka Hirokawa
• MGI ID: MGI:1888955
• Synonyms: kif5C-
• Gene: Kif5c Location: Chr2:49509310-49664790 bp, + strand Genetic Position: Chr2, 28.68 cM, cytoband C
• Alliance: Kif5c^tm1Noh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:64206
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The exon encoding the ATP-binding motif (P-loop) was replaced with pPGKneopA. (J:64206)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif5c Mutation: 47 strains or lines available

References

• Original: J:64206 Kanai Y, et al., KIF5C, a novel neuronal kinesin enriched in motor neurons. J Neurosci. 2000 Sep 1;20(17):6374-84
• All: 1 reference(s)