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Fli1tm1Adh
Targeted Allele Detail
Nomenclature
Symbol: Fli1tm1Adh
Name: Friend leukemia integration 1; targeted mutation 1, Adam Hart
MGI ID: MGI:1888942
Synonyms: Fli-1-, Fli-1LZ, FliresZ, FliresZ-(Fli-1LZ)
Gene: Fli1  Location: Chr9:32422204-32542861 bp, - strand  Genetic Position: Chr9, 17.74 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64178
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 69 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fli1 Mutation:  5 strains or lines available
References
Original:  J:64178 Hart A, et al., Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia. Immunity. 2000 Aug;13(2):167-77
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory