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Timp2tm1Jjc
Targeted Allele Detail
Nomenclature
Symbol: Timp2tm1Jjc
Name: tissue inhibitor of metalloproteinase 2; targeted mutation 1, John J Caterina
MGI ID: MGI:1888709
Synonyms: Timp-2-
Gene: Timp2  Location: Chr11:118301069-118355740 bp, - strand  Genetic Position: Chr11, 83.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64002
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of exons 2 and 3 with a neomycin cassette. (J:64002)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Timp2 Mutation:  8 strains or lines available
References
Original:  J:64002 Caterina JJ, et al., Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2(Timp-2) gene alters proMMP-2 activation. J Biol Chem. 2000 Aug 25;275(34):26416-22
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory