Inhba^tm1Zuk
Targeted Allele Detail

Summary

• Symbol: Inhba^tm1Zuk
• Name: inhibin beta-A; targeted mutation 1, Martin M Matzuk
• MGI ID: MGI:1861957
• Synonyms: actbetaA^ml, Inhba-
• Gene: Inhba Location: Chr13:16186436-16206206 bp, + strand Genetic Position: Chr13, 5.85 cM
• Alliance: Inhba^tm1Zuk page

Cellular defects in the epididymides of the Inhba^tm1Zuk/Inhba^tm1Zuk mouse

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:23923
• Parent Cell Line: AB2.1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A PGK hprt cassette replaced exon 2 of the gene. (J:23923)

Expression

In Mice Carrying this Mutation:	30 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	28 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Inhba Mutation: 31 strains or lines available

References

• Original: J:23923 Matzuk MM, et al., Functional analysis of activins during mammalian development [see comments]. Nature. 1995 Mar 23;374(6520):354-6
• All: 25 reference(s)