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Inpp5dtm1Dmt
Targeted Allele Detail
Nomenclature
Symbol: Inpp5dtm1Dmt
Name: inositol polyphosphate-5-phosphatase D; targeted mutation 1, Dan Dumont
MGI ID: MGI:1861956
Synonyms: Ship -, SHIP-1-, SHIP1-
Gene: Inpp5d  Location: Chr1:87620312-87720507 bp, + strand  Genetic Position: Chr1, 44.44 cM, cytoband C5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:72477
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced all of exon 1 and part of intron 1. (J:72477)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Inpp5d Mutation:  63 strains or lines available
References
Original:  J:72477 Liu Q, et al., The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling. J Exp Med. 1998 Oct 5;188(7):1333-42
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/19/2017
MGI 6.10
The Jackson Laboratory