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Itgb7tm1Cgn
Targeted Allele Detail
Nomenclature
Symbol: Itgb7tm1Cgn
Name: integrin beta 7; targeted mutation 1, University of Cologne
MGI ID: MGI:1861953
Synonyms: beta7-, Itgbtm1Ctg
Gene: Itgb7  Location: Chr15:102215995-102231935 bp, - strand  Genetic Position: Chr15, 57.39 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:34306
Parent Cell Line:  BL/6-III (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced part of exon 12 and all of exons 13 and 14, which encode the transmembrane and part of the extracellular domains. (J:34306)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Itgb7 Mutation:  31 strains or lines available
References
Original:  J:34306 Wagner N, et al., Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue. Nature. 1996 Jul 25;382(6589):366-70
All:  37 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/21/2015
MGI 5.21
The Jackson Laboratory