About   Help   FAQ
Ccr5tm1Kuz
Targeted Allele Detail
Nomenclature
Symbol: Ccr5tm1Kuz
Name: chemokine (C-C motif) receptor 5; targeted mutation 1, William A Kuziel
MGI ID: MGI:1861911
Synonyms: CCR5-, CCR5 KO, Cmkbr5tm1Kuz
Gene: Ccr5  Location: Chr9:124121543-124147699 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64293
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe exon containing the entire coding region was replaced with a neomycin resistance gene inserted by homologous recombination. (J:84243)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Ccr5 Mutation:  5 strains or lines available
References
Original:  J:64293 Huffnagle GB, et al., Cutting edge: Role of C-C chemokine receptor 5 in organ-specific and innate immunity to Cryptococcus neoformans. J Immunol. 1999 Nov 1;163(9):4642-6
All:  127 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory