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Cdk5tm1Kul
Targeted Allele Detail
Nomenclature
Symbol: Cdk5tm1Kul
Name: cyclin-dependent kinase 5; targeted mutation 1, Ashok B Kulkarni
MGI ID: MGI:1861809
Synonyms: Cdk5 (-)
Gene: Cdk5  Location: Chr5:24418250-24423530 bp, - strand  Genetic Position: Chr5, 11.73 cM, cytoband A3-B1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64289
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of part of exon III, exons IV and V with a neomycin cassette. (J:64289)
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 24 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cdk5 Mutation:  5 strains or lines available
References
Original:  J:64289 Ohshima T, et al., Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):11173-8
All:  34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory