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Targeted Allele Detail
Symbol: Cux1tm2Ejn
Name: cut-like homeobox 1; targeted mutation 2, Ellis J Neufield
MGI ID: MGI:1861702
Synonyms: deltaC
Gene: Cux1  Location: Chr5:136248135-136567490 bp, - strand  Genetic Position: Chr5, 75.96 cM
Germline Transmission:  Earliest citation of germline transmission: J:74660
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsPart of exon 20 was deleted and a neomycin resistance cassette was inserted into intron 20. This allele expresses a mutant protein with a deletion in the C terminus, including the homeodomain. (J:74660)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cux1 Mutation:  70 strains or lines available
Original:  J:74660 Luong MX, et al., Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility. Mol Cell Biol. 2002 Mar;22(5):1424-37
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory