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Il1r1tm1Imx
Targeted Allele Detail
Nomenclature
Symbol: Il1r1tm1Imx
Name: interleukin 1 receptor, type I; targeted mutation 1, Immunex Research and Development Corporation
MGI ID: MGI:1861112
Synonyms: IL-1R-, IL-1R1-, Il1r1tm1jmx, IL-1RI KO, Il1rtm1Imx, IL-R1-, RIko
Gene: Il1r1  Location: Chr1:40225080-40316177 bp, + strand  Genetic Position: Chr1, 18.81 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:43088
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 30 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Il1r1 Mutation:  6 strains or lines available
References
Original:  J:43088 Glaccum MB, et al., Phenotypic and functional characterization of mice that lack the type I receptor for IL-1. J Immunol. 1997 Oct 1;159(7):3364-71
All:  170 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory