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Tfamtm1Lrsn
Targeted Allele Detail
Nomenclature
Symbol: Tfamtm1Lrsn
Name: transcription factor A, mitochondrial; targeted mutation 1, Nils-Goran Larsson
MGI ID: MGI:1860962
Synonyms: TfamloxP
Gene: Tfam  Location: Chr10:71225464-71238280 bp, - strand  Genetic Position: Chr10, 36.83 cM, cytoband B5
Skeletal muscle analysis of Tfamtm1Lrsn/Tfamtm1Lrsn Myl1tm1(cre)Sjb/Myl1+ mice

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46387
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tfam Mutation:  3 strains or lines available
References
Original:  J:46387 Larsson NG, et al., Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice [see comments]. Nat Genet. 1998 Mar;18(3):231-6
All:  36 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory