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MipCts
Spontaneous Allele Detail
Summary
Symbol: MipCts
Name: major intrinsic protein of lens fiber; cataract and small eye
MGI ID: MGI:1860482
Synonyms: cataract Shionogi, cs
Gene: Mip  Location: Chr10:128061707-128067681 bp, + strand  Genetic Position: Chr10, 76.49 cM, cytoband D1
Alliance: MipCts page
Mutation
origin
Strain of Origin:  Jcl:ICR
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsThis spontaneous mutation is a C-to-T transition in exon 2 results in a leucine to phenylalanine mutation at amino acid 168 (p.L168F). (J:196356)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mip Mutation:  28 strains or lines available
References
Original:  J:24627 Ohotori H, et al., Small Eye and Cataract, a new dominant mutation in the mouse. Jikken Dobutsu. 1968;17(3):91-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory