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Thtm1Srt
Targeted Allele Detail
Nomenclature
Symbol: Thtm1Srt
Name: tyrosine hydroxylase; targeted mutation 1, Suzanne Roffler-Tarlov
MGI ID: MGI:1860480
Synonyms: Th-, TH-null
Gene: Th  Location: Chr7:142892752-142931128 bp, - strand  Genetic Position: Chr7, 88.06 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:54692
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Th Mutation:  27 strains or lines available
References
Original:  J:54692 Rios M, et al., Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase. J Neurosci. 1999 May 1;19(9):3519-26
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory