About   Help   FAQ
Slc30a3tm1Rpa
Targeted Allele Detail
Nomenclature
Symbol: Slc30a3tm1Rpa
Name: solute carrier family 30 (zinc transporter), member 3; targeted mutation 1, Richard D Palmiter
MGI ID: MGI:1859820
Synonyms: Znt3-, ZnT3
Gene: Slc30a3  Location: Chr5:31086106-31108237 bp, - strand  Genetic Position: Chr5, 16.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:53059
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 through 4 were replaced with a cassette containing nuclear lacZ and neo. Encoded protein was undetectable in brain homogenates from homozygous mutant mice via Western blot analysis. Beta-galactosidase expression was used to observe the activity of the endogenous promoter. (J:53059)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc30a3 Mutation:  1 strain or line available
References
Original:  J:53059 Cole TB, et al., Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1716-21
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/25/2015
MGI 5.21
The Jackson Laboratory