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Terttm1Fish
Targeted Allele Detail
Nomenclature
Symbol: Terttm1Fish
Name: telomerase reverse transcriptase; targeted mutation 1, Fuyuki Ishikawa
MGI ID: MGI:1859741
Synonyms: mTERT-
Gene: Tert  Location: Chr13:73627001-73649041 bp, + strand  Genetic Position: Chr13, 40.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59858
Parent Cell Line:  JH1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of three exons, encoding a highly conserved motif A, with a neomycin cassette. (J:59858)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tert Mutation:  6 strains or lines available
References
Original:  J:59858 Yuan X, et al., Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice. Genes Cells. 1999 Oct;4(10):563-72
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory