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Hbath-J
Chemically induced Allele Detail
Summary
Symbol: Hbath-J
Name: hemoglobin alpha chain complex; alpha thalassemia Jackson
MGI ID: MGI:1858115
Synonyms: alphaMD
Gene: Hba  Location: unknown  Genetic Position: Chr11, cytoband A
Mutation
origin
Strain of Origin:  C57BL/6J x Triethyllenemelamine-treated male
Mutation
description
Allele Type:    Chemically induced (other)
Mutation:    Intergenic deletion
  Hbath-J involves 6 genes/genome features (Rhbdf1, Mpg, Nprl3 ...) View all
 
Mutation detailsThis mutation was shown to be a deletion that included the Hba-x, Hba-a1 and Hba-a2 genes (J:32654). The Mpg, Rhbdf1 and Phg genes are also included in the deletion region (J:29665). (J:29665, J:32654)
Inheritance:    Codominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Hba Mutation:  10 strains or lines available
Notes
The mutation was induced in a male mouse by triethyllenemelamine.
References
Original:  J:45721 Whitney JB, et al., New mutants and biochemical variants: Alpha thalassemia. Mouse News Lett. 1978;58:47-48
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory