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Cryaatm1Wawr
Targeted Allele Detail
Nomenclature
Symbol: Cryaatm1Wawr
Name: crystallin, alpha A; targeted mutation 1, Eric F Wawrousek
MGI ID: MGI:1858025
Synonyms: alphaA, alphaA-, alphaAKO-127
Gene: Cryaa  Location: Chr17:31677945-31681724 bp, + strand  Genetic Position: Chr17, 17.09 cM, cytoband A3-B
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Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:38210
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Inheritance:    Recessive
Phenotypes
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Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cryaa Mutation:  4 strains or lines available
References
Original:  J:38210 Brady JP, et al., Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin. Proc Natl Acad Sci U S A. 1997 Feb 4;94(3):884-9
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory