About   Help   FAQ
Csrp3tm1Crni
Targeted Allele Detail
Nomenclature
Symbol: Csrp3tm1Crni
Name: cysteine and glycine-rich protein 3; targeted mutation 1, Pico Caroni
MGI ID: MGI:1858015
Synonyms: MLP-
Gene: Csrp3  Location: Chr7:48830398-48848051 bp, - strand  Genetic Position: Chr7, 31.11 cM, cytoband B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:38213
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced a genomic fragment containing exon 2. Northern blot analysis on RNA derived from heart of homozygous mice demonstrated that no detectable transcript was produced from this allele. Western blot analysis on extracts derived from heart tissue confirmed that no stable protein was made from this allele. (J:38213)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 16 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csrp3 Mutation:  1 strain or line available
References
Original:  J:38213 Arber S, et al., MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell. 1997 Feb 7;88(3):393-403
All:  27 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/17/2015
MGI 5.21
The Jackson Laboratory