About   Help   FAQ
Ctnnb1tm1Mmt
Targeted Allele Detail
Nomenclature
Symbol: Ctnnb1tm1Mmt
Name: catenin (cadherin associated protein), beta 1; targeted mutation 1, Makoto M Taketo
MGI ID: MGI:1858008
Synonyms: B-cateninfl3, BcatGOF, beta-catact, beta-catc.a., beta-catenindeltaex3, beta-cateninlox-ex3, beta-cateninloxEx3, beta-catenin/loxP(ex3), beta-catex3, beta-catgof, beta-catloxEx3, Catnb(ex3)fl, Catnb(Flox3, Catnblox(ex3), Catnbtm1Tak, Ctnnb1ex3, Ctnnb1(Ex3)fl, Ctnnb1f(Ex3), Ctnnb1lox(ex3), Ctnnbllox(ex3), Ctnnblox(ex3), GOF
Gene: Ctnnb1  Location: Chr9:120929216-120960507 bp, + strand  Genetic Position: Chr9, 72.19 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58367
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 7 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctnnb1 Mutation:  14 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Melanoma J:155731

Phenotypic Similarity to Human Syndrome: Granulosa cell tumor of the testis (GCTT) J:149060

Phenotypic Similarity to Human Syndrome: Granulosa cell tumor (GCT) J:142150

Phenotypic Similarity to Human Syndrome: Granulosa cell tumor (GCT) J:186144

Phenotypic Similarity to Human Syndrome: Granulosa cell tumor of the testis (GCTT) J:186144

Phenotypic Similarity to Human Syndrome: Salivary Gland Squamous Cell Carcinoma J:199091

References
Original:  J:58367 Harada N, et al., Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J. 1999 Nov 1;18(21):5931-42
All:  251 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory